Benzalkonium chloride corneal toxicity post-cataract surgery
نویسندگان
چکیده
منابع مشابه
Corneal toxicity secondary to inadvertent use of benzalkonium chloride preserved viscoelastic material in cataract surgery.
AIMS To study the long term toxic effects of intraocular benzalkonium chloride (BAC). METHODS 19 patients exposed to intraocular BAC preserved viscoelastic during cataract surgery in February 1999 developed severe striate keratopathy immediately postoperatively. 16 patients, including two who underwent penetrating keratoplasty, were studied in the period April to June 2000. Ocular symptoms, v...
متن کاملCLINICAL SCIENCE Corneal toxicity secondary to inadvertent use of benzalkonium chloride preserved viscoelastic material in cataract surgery
Aims: To study the long term toxic effects of intraocular benzalkonium chloride (BAC). Methods: 19 patients exposed to intraocular BAC preserved viscoelastic during cataract surgery in February 1999 developed severe striate keratopathy immediately postoperatively. 16 patients, including two who underwent penetrating keratoplasty, were studied in the period April to June 2000. Ocular symptoms, v...
متن کاملCorneal neurotoxicity due to topical benzalkonium chloride.
PURPOSE The aim of this study was to determine and characterize the effect of topical application of benzalkonium chloride (BAK) on corneal nerves in vivo and in vitro. METHODS Thy1-YFP+ neurofluorescent mouse eyes were treated topically with vehicle or BAK (0.01% or 0.1%). Wide-field stereofluorescence microscopy was performed to sequentially image the treated corneas in vivo every week for ...
متن کاملInfluence of alkyl chain length of benzalkonium chloride on acute corneal epithelial toxicity.
PURPOSE To evaluate acute corneal epithelial toxicity induced by benzalkonium chloride (BAC) homologs with different alkyl chain lengths using an in vivo electrophysiological method. METHODS BAC homologs with C12, C14, and C16 alkyl chain lengths were used at concentrations of 0.0025%, 0.005%, and 0.01%, respectively. Cytotoxicity of BAC homologs on the normal rabbit corneal epithelial cells ...
متن کاملInfluence of different additives and their concentrations on corneal toxicity and antimicrobial effect of benzalkonium chloride.
PURPOSE The aim of this study was to examine the ophthalmic additives responsible for modulating acute corneal epithelial toxicity induced by benzalkonium chloride (BAC) and investigate the ability of polyoxyethylene hydrogenated castor oil 40 (HCO-40) and polysorbate 80 (PS-80) to reduce the corneal toxicity and antimicrobial effects of BAC. METHODS Cytotoxicity of the additives, which inclu...
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ژورنال
عنوان ژورنال: Asian Journal of Ophthalmology
سال: 2020
ISSN: 1560-2133,1560-2133
DOI: 10.35119/asjoo.v17i1.620